Lady Margaret Beaufort (1443)
Beaufort was an English noblewoman, wife of Edmund Tudor, and the mother of Henry VII, founder of the Tudor Dynasty. She gave birth to Henry at 13, shortly after being widowed, and developed a close bond with her only child. Renowned for her philanthropy, she endowed professorships of divinity at Oxford and Cambridge and with the help of her confessor, John Fisher, founded Christ's College and St. John's College, Cambridge. She later acted as regent for Henry VIII.